Electrometallurgy Today, 2023, №01



2023 №01 (02)

DOI of Article 10.37434/sem2023.01.03

2023 №01 (04)

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Electrometallurgy Today (Sovremennaya Elektrometallurgiya), 2023, #1, 16-24 pages

Electron beam technology for obtaining nanostructured silver coatings on powders of inorganic and organic substances, medicinal nanocomposite substances and their research

G.G. Didikin¹, S.B. Bilous², I.S. Kovinskyi¹, O.O. Ilkov³

¹E.O. Paton Electric Welding Institute of the NAS of Ukraine 11 Kazymyr Malevych Str., 03150, Kyiv, Ukraine. E-mail: office@paton.kiev.ua
²Danylo Halytsky Lviv National Medical University. 69 Pekarska Str., 79010, Lviv, Ukraine.
³Institute of Animal Biology of the National Academy of Sciences of Ukraine. 38 Vasyl Stus Str., 79034, Lviv, Ukraine.

Abstract
The technological schemes of the process of electron beam evaporation and condensation and examples of their use for the synthesis of nanocomposites based on inorganic and organic carriers, as well as methodological and experimental development of antimicrobial substances based on Ag nanoparticles are considered. The biological and physicochemical properties of silver nanoparticles and the effectiveness of antimicrobial action of a composite with silver nanoparticles on the surface of a medical product were evaluated. Examples of possible use of antimicrobial drugs for medical purposes are given. The bactericidal effect of the composite against representatives of opportunistic pathogens that can cause hospital-acquired infections was revealed. Evaluation of the antimicrobial and cytotoxic effects of composites containing silver nanoparticles, allows us recommending it for the development of prophylactic and therapeutic agents in various forms of release for external and internal use. Ref. 7, Tabl. 1, Fig. 14.
Keywords: electron beam physical deposition in vacuum; silver; nanoparticles; X-ray phase analysis; scanning electron microscopy; transmission electron microscopy; dynamic light scattering; bactericidality; cytotoxicity; metronidazole; levofloxacin

Received 01.11.2022

References

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