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Зварювання та споріднені технології для відновлення України: Тези допов. конф. під ред. О.Т. Зельніченка. Київ, ТОВ «Видавничий Дім «Патон», 2025, с. 48-48

Functional silver and copper nanocoatings on medical implants deposited by the EB-PVD method

Gornostai O.V., Khokhlov M.A., Stelmakh Y.A., Khokhlova J.A.

ІЕЗ ім. Є.О. Патона НАН України. 03150, м. Київ, вул Казимира Малевича, 11.

One of the critical issues leading to postoperative complications and prolonged recovery time especially in patients with combat-related injuries accompanied by blood loss, systemic exhaustion, and immune suppression is bacterial contamination of implant surfaces. As a result, so-called prosthetic infections often require long-term antibacterial therapy and may necessitate implant removal. Existing prevention and treatment strategies are not always effective, highlighting the need for novel approaches to inhibit bacterial adhesion and biofilm formation on implantable medical devices.
The use of metal nanoparticles, particularly silver and copper, is a promising strategy due to their pronounced antimicrobial properties. Currently, several specialized PVD methods have been developed and are classified based on the energy source used.

Список літератури

1. Gornostai, O., Khokhlov, M., Stelmakh, Y. et al. (2024) Increasing the productivity of EBPVD process for obtaining of Ag and Cu antimicrobial nanocoating on Mg-based alloy implants in osteosynthesis. In: Proc. of 2024 IEEE 14th Inter. Conf. on Nanomaterials: Applications & Properties (NAP), Riga, Latvia, 2024, 1–4. DOI: https://doi.org/10.1109/NAP62956.2024.10739760
2. Savelyev, Yu., Gonchar, A., Movchan, B. О. et al. (2017) Antibacterial polyurethane materials with silver and copper nanoparticles. Materials Today: Proceedings, 4(1), 87–94. DOI: https://doi.org/10.1016/j.matpr.2017.01.196
3. Minarchenko, V.M., Kutsyk R.V., Kovalska, N.P. et al. (2017) Effect of silver nanoparticles on the physical and chemical properties of plant oil sand the antimicrobial activity. Biotechnologia Acta, 10(6), 35–44. DOI: https://doi.org/10.15407/biotech10.06.035

Functional silver and copper nanocoatings on medical implants deposited by the EB-PVD method

Gornostai O.V., Khokhlov M.A., Stelmakh Y.A., Khokhlova J.A.

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